Brainmap: Dissecting neural circuits underlying behaviors relevant to psychiatric disease in animal models

Wednesday, November 20, 2013 - 12:00
Seminar room 2204, 149 13th St., Charlestown Navy Yard

Kay Tye

The ability to differentiate between positive and negative environmental stimuli is critical to an animal's survival.  However, the  neural circuits that endow the brain with the ability to differentiate positive and negative motivationally significant stimuli have been difficult to disentangle and represent one of the most important fundamental neuroscience questions today. The development and application of optogenetic approaches has allowed us to probe the causal relationships between activity in specific circuit elements and animal behavior relevant to psychiatric disease states such as anxiety, addiction and depression.  In this seminar, Kay Tye will discuss her research on the corticolimbic circuits that mediate valence processing.