@ Martinos Center and Tufts University

Original Articles and Reviews

2008

• Nieuwland MS, Kuperberg GR. When the truth isn't too hard to handle: An Event-Related Potential study on the Pragmatics of Negation. Psychological Science. In press. [pdf]

• Kuperberg GR, West WC, Lakshmanan BM, Goff DC. fMRI reveals neuroanatomical dissociations during semantic integration in schizophrenia. Biological Psychiatry. In press.[pdf]

• Ditman T, Holcomb PJ, Kuperberg GR. Time travel through language: temporal shifts rapidly decrease information accessibility during reading. Psychonomic Bulletin & Review. In press. [pdf]

• Kuperberg GR, Kreher DA, Ditman T. What can event-related potentials tell us about language, and perhaps even thought, in schizophrenia? International Journal of Psychophysiology, 'Language and Psychophysiology' Special Issue. In press. [pdf]

• Kuperberg GR. Building meaning in schizophrenia. EEG and Clinical Neuroscience. 'Psychosis', Special Issue. In press.

• Sitnikova T, Holcomb PJ, Kuperberg GR. Two neurocognitive mechanisms of semantic integration during the comprehension of visual real-world events. Journal of Cognitive Neuroscience 2008; In press. [pdf]

• Kuperberg GR, Lakshmanan BM, Greve DN, West WC. Task and semantic relationship influence both the polarity and localization of hemodynamic modulation during lexico-semantic processing. Human Brain Mapping 2008; 29(5). [pdf]

• Kuperberg GR, Sitnikova T, Lakshmanan BM. Neuroanatomical distinctions within the semantic system during sentence comprehension: evidence from functional Magnetic Resonance Imaging. NeuroImage 2008; 40:367-388. [pdf]

• Kreher DA, Holcomb PJ, Goff DC, Kuperberg GR. Neural evidence for faster and further automatic spreading activation in schizophrenic thought disorder. Schizophrenia Bulletin 2008; 34:473-482. [pdf]

2007

• Ditman T & Kuperberg, GR. The time course of building discourse coherence in schizophrenia: an ERP investigation. Psychophysiology 2007; 44:991-1001. [pdf]

• Ditman T, Holcomb PJ, Kuperberg GR. An investigation of concurrent ERP and self-paced reading methodologies. Psychophysiology 2007; 44:927-935. [pdf]

• Wisco JJ, Kuperberg GR, Manoach D, Quinn B, Busa E, Fischl B, Heckers S, Sorensen G. Abnormal cortical folding patterns within Broca’s area in schizophrenia: Evidence from structural MRI. Schizophrenia Research 2007; 94:317-327.[pdf]

• Ditman T, Holcomb PJ, Kuperberg GR. The contributions of lexico-semantic and discourse information to the resolution of ambiguous categorical anaphors. Language and Cognitive Processes 2007; 22:793-827. [pdf]

• Kuperberg GR, Deckersbach T, Holt DJ, Goff DC, West WC. Increased temporal and prefrontal activity in response to semantic associations in schizophrenia. Archives of General Psychiatry 2007; 64: 138-151. [pdf]

• Kuperberg GR, Kreher DA, Sitnikova T, Caplan D, Holcomb PJ. The role of animacy and thematic relationships in processing active English sentences: Evidence from event-related potentials. Brain and Language 2007; 100: 223-238. [pdf]

  See also accompanying commentary: H. Kolk & D. Chwilla, "Late positivities in unusual situations".

• Kuperberg GR. Neural mechanisms of language comprehension: Challenges to syntax. Brain Research (Special Issue) 2007; 1146:23-49. Epub 2006 Dec 2. [pdf]

2006

• Kuperberg GR, Lakshmanan BM, Caplan D, Holcomb PJ. Making sense of discourse: an fMRI study of causal inferencing across sentences. NeuroImage 2006; 33: 343-361. [pdf]

• Kreher DA, Holcomb PJ, Kuperberg GR. An electrophysiological investigation of indirect semantic priming. Psychophysiology 2006; 43:550-563. [pdf]

• Kuperberg GR, Kreher DA, Goff DC, McGuire P, David A. Building up linguistic context in schizophrenia: Evidence from self-paced reading. Neuropsychology 2006; 20: 442-452. [pdf] Building up

• Holt DJ, Titone D, Long S, Goff DC, Cather C, Rauch SL, Judge A, Kuperberg GR. Misattributions of salience in delusional patients with schizophrenia. Schizophrenia Research 2006; 83:247-256. [pdf]

• Sitnikova T, West WC, Kuperberg GR, Holcomb PJ. The neural organization of semantic memory: electrophysiological activity suggests feature-based anatomical segregation. Biological Psychology 2006; 71:326-340. [pdf]

• Kuperberg GR, Sitnikova T, Goff DC, Holcomb PJ. Making sense of sentences in schizophrenia: electrophysiological evidence for abnormal interactions between semantic and syntactic processes. Journal of Abnormal Psychology 2006; 115(2):243-256. [pdf]

• Kuperberg GR, Caplan D, Sitnikova T, Eddy M, Holcomb PJ. Neural correlates of processing syntactic, semantic and thematic relationships in sentences. Language and Cognitive Processes 2006; 21(5):489-530. [pdf]

2003-2005

• Ditman T, Kuperberg GR. A source monitoring account of auditory verbal hallucinations in schizophrenia. Harvard Review of Psychiatry; 2005;13:280-299. [pdf]

• Kuperberg GR, Broome M, McGuire P, David A, Eddy M, Goff DC, West WC, van der Kouwe AJW, Salat DH, Dale AM, Fischl, B. Regionally localized thinning of the cerebral cortex in schizophrenia. Arch Gen Psychiatry 2003; 60:878-88. [pdf]

• Kuperberg GR, Sitnikova T, Caplan D, Holcomb PJ. Electrophysiological distinctions in processing conceptual relationships within simple sentences. Cogn Brain Res 2003; 217:117-29. [pdf]

• Kuperberg GR, Holcomb PJ, Sitnikova T, Greve D, Dale AM, Caplan D. Distinct patterns of neural modulation during the processing of conceptual and syntactic anomalies. J Cogn Neurosci 2003; 15:272-93. [pdf]

• Sitnikova T, Kuperberg GR, Holcomb PJ. Semantic integration in videos of real-world events: an electrophysiological investigation. Psychophysiol 2003; 40:160-64. [pdf]

Prior to 2002

• Sitnikova T, Salisbury DF, Kuperberg GR, Holcomb PJ. Electrophysiological insights into language processing in schizophrenia. Psychophysiol 2002; 39:851-60. [pdf]

• Kuperberg GR, Kerwin R, Murray RM. Developments in the pharmacological treatment of schizophrenia. Expert Opin Investig Drugs 2002;11:1335-41. [pdf]

• Caplan D, Vijayan S, Kuperberg GR, West WC, Waters G, Greve D, Dale A. Vascular responses to syntactic processing: event-related fMRI study of relative clauses. Hum Brain Mapp 2001; 15:26-38. [pdf]

• Kuperberg GR, McGuire PK, Bullmore ET, Brammer MJ, Rabe-Hesketh S, Wright IC, Lythgoe DJ, Williams SC, David AS. Common and distinct neural substrates for pragmatic, semantic, and syntactic processing of spoken sentences: an fMRI study. J Cogn Neurosci 2000; 12:321-41. [pdf]

• Kuperberg GR, McGuire PK, David AS. Sensitivity to linguistic anomalies in spoken sentences: a case study approach to understanding thought disorder in schizophrenia. Psychol Med 2000; 30:345-57. [pdf]

• Kuperberg G, Heckers S. Schizophrenia and cognitive function. Curr Opin Neurobiol 2000;10:205-10. [pdf]

• Kuperberg GR, McGuire PK, David A. Reduced sensitivity to linguistic context in schizophrenic thought disorder: Evidence from online monitoring for words in linguistically-anomalous sentences. J Abnorm Psychol 1998; 107:423-34. [pdf]

• Kuperberg GR, Murray R. Advances in the treatment of schizophrenia. Br J Clin Pract 1996;50:315-23.

Textbooks and Book Chapters

• Osterhout L, Kim A, Kuperberg GR. The Neurobiology of sentence comprehension. To appear in M. Spivey, M. Joannisse, & K. McRae (Eds), The Cambridge Handbook of Psycholinguistics. Cambridge: Cambridge University Press. [pdf]

• Sitnikova T, Holcomb PJ, Kuperberg GR. Neurocognitive mechanisms of human comprehension. In Eds. T. F. Shipley & J. Zacks. Understanding Events: How Humans See, Represent, and Act on Events. Oxford University Press. 2008; 639-683. [pdf]

• Kuperberg GR, Ditman T, Kreher D, Goldberg T. Approaches to Understanding language dysfunction in neuropsychiatric disorders: Insights from the study of schizophrenia. To appear in S. Wood, N. Allen and C. Pantelis (Eds). Handbook of Neuropsychology of Mental Disorders. Cambridge University Press.

• Kuperberg GR. EEG, ERPs, MEG and multimodal imaging: Applications in Psychiatry. In: S Rauch and D Doughtery (eds): Psychiatric Neuroimaging: A Primer for Clinicians, 1st edition, 2004; 117-128, American Psychiatric Publishing, Inc., Arlington. [pdf]

• Kuperberg GR, Caplan D. Language dysfunction in schizophrenia. In R.B. Schiffer, S.M. Rao, and B.S. Fogel (eds): Neuropsychiatry, 2nd edition, 2003: 444-66. Lippincott Williams and Wilkins, Philadelphia, PA. [pdf]

• Kuperberg GR, Lumley J. Final MBBS surgery: Clinical examination and differential diagnosis of common surgical conditions. 2nd edition, 2003 Pastest, Knutsford, Cheshire. [Amazon.co.uk]

• Kuperberg GR, Lumley J. Final MBBS surgery: Clinical examination and differential diagnosis of common surgical conditions. 1st edition, 1995 Pastest, Knutsford, Cheshire [Amazon.com]

Abstracts and Posters

(work already published in full manuscript form is not listed )

• Kuperberg GR, Kreher DA, Goff DC, Swain A, Holt DJ. Selective neural deficits in comprehending emotional information within social vignettes in schizophrenia. 63rd annual meeting of the Society of Biological Psychiatry. [Abstract] [Poster]

• Kuperberg GR, Choi A, Cohn N, Paczynski M, Ditman T, Holcomb PJ, Jackendoff R. An ERP study of the timecourse of complement coercion. CUNY 2008 & CNS 2008. [Abstract] [Poster]

• De Grauwe S, Swain A, Ditman T, Holcomb PJ, Kuperberg GR. Electrophysiological insights into the processing of nominal metaphors. Cogn Neurosci Suppl. 2008. [Abstract] [Poster]

• Nieuwland MS, Kuperberg GR. When the truth isn't too hard to handle: An Event-related potential study of pragmatics of negation. CUNY 2008 & CNS 2008. [Poster]

• Ditman T, Kuperberg GR. An ERP examination of lexico-semantic and contextual influences across sentence boundaries in schizophrenia. Cogn Neurosci Suppl. 2008.

• Ditman T, Holcomb PJ, Kuperberg GR. An electrophysiological examination of the use of temporal cues during discourse comprehension. Psychonomic Society. 2008.

• Sitnikova T, Paczynski M, Kuperberg GR. Context motivates comprehenders attempts to make sense of novel events: Evidence from event-related potentials. [abstract]. J Cogn Neurosci Suppl. 2007.

• De Grauwe S, Davis LJ, Ditman T, Paczynski M, Holcomb PJ, Kuperberg GR. Electrophysiological insights into the processing of nominal metaphors. Cogn Neurosci Suppl. 2007. [Poster]

• Holt DJ, West WC, Lakshmanan BM, Rauch SL, Kuperberg GR. Neural correlates of emotional expectancy during sentence comprehension. Cogn Neurosci Suppl. 2007. [Poster]

• Kreher DA, Holcomb PJ, Choi S, Goff DC, Kuperberg GR. The influence of task on automatic semantic priming in schizophrenia: Evidence from event-related potentials. Cogn Neurosci Suppl. 2007. [Poster]

• Stanczak L, Caplan D, Waters G, Babbitt L, Lee JM, Kuperberg GR, Perlmutter N. BOLD signal correlates of semantic plausibility as a function of working memory and task demand. Cogn Neurosci Suppl. 2007. [Poster]

• Paczynski M, Ditman T, Okano K, Kuperberg GR. Drawing inferences during discourse comprehension: An ERP study. Cogn Neurosci Suppl. 2007. [Poster]

• Ditman T, Holcomb PJ, Kuperberg GR. The influence of discourse focus on anaphor resolution: A simultaneous self-paced reading and ERP investigation. Cogn Neurosci Suppl. 2007. [Poster]

• Kuperberg GR, Lakshmanan BM, Goff DC, West WC. Double Dissociations in hemodynamic modulation during the build-up of concrete and abstract meaning in schizophrenia: Evidence from fMRI. Schizophrenia Research. 2007. [Poster]

• Holt DJ, Lakshmanan BM, Freudenreich O, Goff DC, Rauch SL, Kuperberg GR. An event-related functional MRI study of neural responses to social information in schizophrenia. [abstract]. The EEG and Clinical Neuroscience Society meeting 2006.

• Sitnikova T, West WC, Holcomb PJ, Kuperberg GR. Functional neuroanatomy of abnormal real-world comprehension in schizophrenia. Human Brain Mapping, Suppl. 2006. [Abstract]

• Holt DJ, West WC, Lakshmanan B, Rauch S, Kuperberg GR. Neural responses to emotionally-salient social information: an event-related functional MRI study. Human Brain Mapping, Suppl. 2006. [Abstract]

• Geyer A, Holcomb PJ, Kuperberg GR, Perlmutter N. Plausibility and sentence comprehension. An ERP Study. Cogn Neurosci Suppl. 2006. [Abstract] [Poster]

• Sitnikova T, West WC, Kuperberg GR. Cortico-striatal dysfunction during real-world world comprehension in schizophrenia. Cogn Neurosci Suppl. 2006. [Abstract] [poster]

• Packynski M, Kreher DA, Ditman T, Holcomb PJ, Kuperberg GR. Electrophysiological evidence for the role of animacy and lexico-semantic associations in processing nouns within passive structures. Cogn Neurosci Suppl. 2006. [Abstract] [poster]

• Kuperberg GR, Gulabani D, Goff DC, Blais K, Caplan D, Holcomb PJ. From the Knight to the Right: an event-related fMRI study of schizophrenic thinking. Human Brain Mapping, Suppl. 2005. [Abstract] [poster]

• Sitnikova T, Cotton J, West WC, Holcomb PJ, Kuperberg GR. Comprehension of real-world events in schizophrenia: an electrophysiological perspective. J Cogn Neurosci Suppl. 2005 [Abstract] [poster]

• Holt DJ, Lynn S, Kreher D,  Rauch SL, Holcomb PJ, Kuperberg GR. Neurophysiological correlates of reading emotional sentences. J Cogn Neurosci Suppl. 2005 [Abstract] [poster]

• Kuperberg GR, Caplan D, Eddy M, Cotton J, Holcomb PJ. Electrophysiological correlates of processing causal relationships between sentences. J Cogn Neurosci Suppl. 2004. [abstract] [poster]

• Sitnikova T, Coty A, Robakis D, Holcomb PJ, Kuperberg GR, West WC. fMRI correlates of comprehending real-world events. Neuroscience, the Society for Neuroscience's 34th Annual Meeting 2004. [abstract]

• Holt DJ, Titone D, Long S, Cather C, Judge A, Rauch SL, Goff DC, Kuperberg GR. The evaluation of emotional salience in delusional patients with schizophrenia. Biological Psychiatry Suppl. 2004. [abstract]

• Kuperberg GR, Goff DC, Eddy M, Rosen B, Sitnikova T, Caplan D. Abnormal modulation of cortical networks during language processing in schizophrenia. J Cogn Neurosci Suppl 83 2002. [abstract]