My research
interests and expertise revolve around brain mechanisms involved in pain
control. I have performed clinical research studies where I used neuroimaging
to investigate the neural correlates to different treatments for fibromyalgia
pain and the role of psychiatric comorbidity. My line of research is currently
focused on psychological influences on pain
regulation, in particular placebo analgesia.
Original research articles in refereed scientific journals
1. Jensen K, Petrovic P, Kerr C, Kirsch I, Raicek J,
Cheetham A, Spaeth R, Cook A, Gollub RL, Kong J*, Kaptchuk T*. Sharing pain and
relief: Neural correlates of physicians during treatment of patients, Molecular Psychiatry, In Press.
2. Jensen K, Kaptchuk TJ, Kirsch I, Raicek J, Lindstrom
KM, Berna C, Gollub RL, Ingvar M, Kong J. Non-conscious Activation of Placebo
and Nocebo Pain Responses. Proc Natl Acad Sci (PNAS) 2012, 109(39), 15959-64.
3. Hall K, Lembo A, Kirsch I, Ziogas D, Douaiher J, Jensen K,
Conboy L, Kelley J, Kaptchuk T, Kokkotou E. COMT val158met Polymorphism
Predicts Placebo Effect in Irritable Bowel Syndrome. PLoS One, In press.
4. Mohan R*, Jensen K*, Petkova V, Dey A, Barnsley N,
Ingvar M, McAuley J, Moseley L*, Ehrsson H*. Pain intensity is maintained
during the rubber hand illusion. PLoS One,
In press.
5. Petzke F*, Jensen K*, Kosek E, Choy E, Carville S,
Fransson P, Williams S, Marcus H, Mainguy Y, Ingvar M, Gracely RH. Using fMRI
to evaluate the effects of milnacipran on central pain processing in patients
with fibromyalgia. Scand J Pain, In press.
6. Wicksell R, Kemani M, Jensen K, Kosek E, Kadetoff D,
Sorjonen K, Ingvar M, Olsson G. Acceptance and Commitment Therapy for
Fibromyalgia: A randomized controlled trial. Eur J Pain, In press.
7. Jensen K, Kosek E, Wicksell R, Kemani M, Olsson G,
Merle JV, Kadetoff D, Ingvar M. Cognitive Behavioral Therapy increases
pain-evoked activation of the prefrontal cortex in patients with fibromyalgia. Pain
2012; 153(7): 1495-1503.
8. Jensen K, Berna C, Loggia ML, Wasan AD, Edwards RR,
Gollub RL. The use of functional neuroimaging to evaluate psychological and
other non-pharmacological treatments for pain. Neurosci Lett. 2012;
520(2): 156-164.
9. Jensen K, Loitoile R, Kosek E, Petzke F, Carville S,
Fransson P, Marcus H, Williams S, Choy E, Mainguy Y, Vitton O, Gracely RH,
Gollub RL, Ingvar M, Kong J. Patients With Fibromyalgia Display Less Functional
Connectivity In The Brain’s Pain Inhibitory Network, Mol Pain 2012;
8(1):32.
10. Loggia ML*, Jensen K*, Gollub RL, Wasan AD, Edwards
RR, Kong J. The Catechol-O-Methyltransferase (COMT) valmet Polymorphism Affects
Brain Responses to Repeated Painful Stimuli. PLoS One 2011;
6(11):e27764.
11. Linnman C*, Beucke JC*, Jensen K, Gollub RL, Kong J.
Sex similarities and differences in pain-related periaqueductal gray
connectivity. Pain 2012; 153(2):444-54.
12. Jensen K, Ingvar M, Petzke F, Carville S, Fransson P,
Choy E, Williams SCR, Marcus H, Mainguy Y, Gracely RH, Kosek E. Anxiety and
depressive symptoms in fibromyalgia are related to low health esteem but not to
sensitivity or cerebral processing of pain. Arthritis & Rheumatism
2010; 62(11):3488-3495.
13. Zyloney C, Jensen K, Gollub RL, LaViolette P,
Kaptchuk T, Kong J. Imaging the functional connectivity of the Periaqueductal
Gray during verum and sham electroacupuncture treatment. Mol Pain;
16(6):80.
14. Jensen K, Kosek E, Petzke F, Carville S, Fransson P,
Marcus H, Williams SCR, Choy E, Giesecke T, Mainguy Y, Gracely R, Ingvar M.
Evidence of dysfunctional pain inhibition in Fibromyalgia reflected in rACC
during provoked pain. Pain 2009;144(1-2):95-100.
15. Jensen K, Lonsdorf T, Schalling M, Kosek E, Ingvar M.
Increased Sensitivity to Thermal Pain Following a Single Opiate Dose Is
Influenced by the COMT val158met Polymorphism. PLoS One 2009;4(6):e6016.
16. Kosek E, Jensen K, Lonsdorf T, Schalling M, Ingvar M.
Genetic variation in the serotonin transporter gene (5-HTTLPR, rs25531)
influences the analgesic response to the short acting opioid Remifentanil in
humans. Mol Pain 2009;5(1):37.
Review articles, book chapters, etc.
1. Jensen K. Brain
mechanisms in pain regulation. Ph.D. thesis. Karolinska University Press.
Stockholm: 2009. ISBN 978-91-7409-646-0
2. Loggia ML, Jensen K. Pain imaging in the human brain. Book Chapter. Ed: Seeman P, Madras
B. Imaging of the Human Brain in Health and Disease: Neuroscience-Net 2011.
Number of pages: 32.
3. Jensen K. Kognitiv
beteendeterapi. Book Chapter. Ed: Kosek E, Nisell R, Lampa J. Smärta och
inflammation vid reumatiska sjukdomar: Studentlitteratur: Stockholm. In press
2013. Number of pages: 10.
Other scientific contributions: manuscripts
1. Jensen K, Srinivasan P, Spaeth R, Tan Y, Kosek E,
Petzke F, Carville S, Fransson P, Marcus H, Williams S, Choy E, Vitton O, Gracely
RH, Ingvar M, Kong J. Overlapping structural and functional brain changes in
patients with long-term exposure to chronic pain. Under review.
2. Jensen K, Freiherr J, Frasnelli J, Lundström JN. Pain
processing in health and disease: An ALE meta-analysis of neuroimaging studies
in patients and healthy controls, Under Review.
3. Kong J, Jensen K, Loiotile R, Cheetham A, Wey H-Y, Tan
Y, Rosen B, Smoller J, Kaptchuk TJ, Gollub R. Functional connectivity of the
frontoparietal network predicts cognitive modulation of pain. Under review.
4. Kong J, Spaeth R, Wey H-Y, Cheetham A, Cook A, Jensen K,
Tan Y, Liu H, Wang D, Loggia M, Napadow V, Smoller J, Wasan A, Gollub RL. S1 is
associated with chronic low back pain: a functional and structural MRI study. Under
review.
Original contributions to refereed scientific conferences
2012
1. Jensen K, Seminowicz D, Wiech K, Edwards RR. Cognitive
and Behavioral Interventions - Influence on CNS Pain Processing. 13th Annual
Congress of the American Pain Society (APS), Honolulu, May 17-21. Symposium
speaker
2. Jensen K. Neuroimaging of patients with fibromyalgia and
the neural correlates to non-pharmacological treatments. Excellent Investigator
Award, International symposium of fMRI studies of brain effects of acupuncture,
Beijing China, June 14. Symposium Speaker
3. Jensen K, Petrovic P, Kerr C, Kirsch I, Raicek J,
Cheetham A, Spaeth R, Cook A, Gollub RL, Kong J, Kaptchuk T. Physicians
activate their own pain modulatory brain regions during delivery of placebo
analgesia. 18th Annual Meeting of the Organization for Human Brain Mapping
(OHBM). Beijing, China, June 10-14. Poster
4. Jensen K, Srinivasan P, Spaeth R, Tan Y, Kosek E, Petzke
F, Carville S, Fransson P, Marcus H, Williams S, Choy E, Vitton O, Gracely RH,
Ingvar M, Kong J. Overlapping structural and functional brain changes in
patients with long-term exposure to chronic pain. 14th World Congress on Pain,
International Association for the Study of Pain (IASP). Travel Award. Milano,
August 27-31. Poster
2011
5. Jensen K, Loitoile R, Kosek E, Petzke F, Carville S,
Fransson P, Marcus H, Williams S, Choy E, Mainguy Y, Vitton O, Gracely RH,
Gollub RL, Ingvar M, Kong J. Patients With Fibromyalgia Display Less Functional
Connectivity In The Brain’s Pain Inhibitory Network. Society for Neuroscience
(SfN) Annual Congress. Washington D.C., USA, November 12-16. Symposium
Speaker
6. Jensen K, Kosek E, Wicksell R, Kemani M, Olsson G, Merle
JV, Kadetoff D, Ingvar M. Cognitive Behavioral Therapy increases pain-evoked
activation of the prefrontal cortex in patients with fibromyalgia. Pan African
Pain Meeting and Neuro-SIG, Cape Town, South Africa, March
11-13. (Speaker award) Symposium Speaker
7. Jensen K, Kosek E, Wicksell R, Kemani M, Olsson G,
Merle JV, Kadetoff D, Ingvar M. Cognitive Behavioral Therapy increases
pain-evoked activation of the prefrontal cortex in patients with fibromyalgia.
17th Annual Meeting of the Organization for Human Brain Mapping (OHBM). Quebec
City, Canada, June 26-30. Poster
8. Kong J, Jensen K, Loiotile R, Cheetham A, Rosen B,
Smoller J, Kaptchuk TJ, Gollub R. An fMRI study on how contextual learning can
modulate pain perception. Society for Neuroscience Annual Congress, Washington
D.C., USA, November 12-16. Poster
2010
9. Loggia ML*, Jensen K*, Gollub RL, Wasan AD, Edwards RR,
Kong J (*shared first author). The Catechol-O-Methyltransferase (COMT) val/met
Polymorphism Affects Brain Responses to Repeated Painful Stimuli. 13th World
Congress on Pain, International Association for the Study of Pain (IASP).
Montreal, Canada, August 29-Sep 3. Poster
10. Linnman C, Jensen K, Razifar P, Fredrikson M, Långström
B. Dynamical PET imaging of Neurokinin 1 receptors, a proof of principle. 13th
World Congress on Pain, International Association for the Study of Pain (IASP).
Montreal, Canada, August 29-Sep 3. Poster
11. Petzke F*, Jensen K*, Kosek E, Choy E, Carville S,
Fransson P, Williams S, Marcus H, Ingvar M, Gracely R. (*shared first author)
Segregating the effect of antidepressants and placebo in chronic pain. Society
for Neuroscience Annual Congress, San Diego, USA, November 13-17. Poster
Occasional reviewer for the following journals
· Arch Gen Psychiatry
· Cerebral Cortex
· Pain
· Pain Medicine
· Psychiatry Genetics
· BMC Psychiatry
· Arthritis Care &
Research