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Van J Wedeen, MD
Associate Professor in Radiology at Harvard Medical School
Assistant Neuroscientist at Massachusetts General Hospital
Director of Connectomics at Martinos Center
Department of Radiology, MGH
MD, Medicine, Albert Einstein College of Medicine
Building 149, Room 2301
13th Street
Charlestown, MA 02129
Phone:
Fax:
Location:
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DESCRIPTION OF WORK / BIOSKETCH
Development of MRI methods and contrast mechanisms to address biological problems. Past inventions include
• phase contrast flow imaging (1984)
• magnetic resonance angiography with Rheto Meuli (CHUV) (1983-6)
• tensor MRI of myocardial strain (1990)
• MRI of myocardial fiber structure and fiber shortening with WYI Tseng (NTUH) (1993-8)
• diffusion tractography (1995-6)
• high angular resolution diffusion MRI, including Q-ball with Dave Tuch and DSI (1999) (see color icon this page top right)
Other work includes
• MRI dynamic range compression by means of a nonlinear gradient pulse (3D chirp)
• fast 3D MRA by under sampling of k-space
• discovery of displacement encoding with a stimulated echo (DENSE) with Tim Reese (1995)
• balanced diffusion encoding for suppression of eddy current
• co-developed TrackVis environment with Ruopeng Wang (Martinos Ctr)
Present work is focused on discovery with diffusion MRI of new aspects of geometric order in the CNS, including complex path coherence within the cerebral cortex, and organization of cerebral white matter and connectivity across multiple scales.
LINKS
Photo essay in Technology Review on recent work - DSI of neural connectivity
Photo essay in Technology Review on recent work - DSI of neural connectivity
Photo essay in Technology Review on recent work - DSI of neural connectivity in spanish
TrackVis software suite for diffusion MRI visualization
DSI tractography rotating marmoset brain
science story by BBC affiliate
Interview in American Scientist, with images of brain development
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