MOLECULAR IMAGING LABORATORY
Publications |
2012Ifediba M, Moore A. In vivo imaging of the systemic delivery of small interfering RNAWIREs Nanomed Nanobiotechnol 2012. doi: 10.1002/wnan.1158 Ran C, Zhang Z, Hooker J, Moore A. In vivo photoactivation without “light”: use of a Cherenkov radiation to overcome the penetration limit of light. Mol Imaging Biol, 2012, 14:156-162. Yigit M, Moore A, Medarova Z. Magnetic nanoparticles for cancer diagnosis and therapy, Pharm Res, 2012 in press. Kavishwar A, Medarova Z, Moore A. In vivo MR imaging of nanolabeled diabetogenic T cells. Nanotechnology and Nanomedicine in Diabetes, Eds. Le, LA, Hunter, RJ and Preedy VR. CRC Press, Taylor and Francis Group, Science Publishers, Enfield, NH. 2012, Section 4, Chapter 15, pp. 287-304. Ran C, Moore A. Spectral unmixing imaging of “smart” fluorescent probes: an application for the real-time report of amyloid beta species in Alzheimer’s disease. Mol Imaging Biol, 2012, 14:293- 300 PMCID: PMC3229962 Yigit MV, Ghosh SK, Kumar M, Petkova V, Kavishwar A, Moore A*, Medarova Z*. Context-dependent differences in miR-10b breast oncogenesis can be targeted for the prevention and arrest of lymph node metastasis, Oncogene, 2012, in press. * - corresponding authors. Uppal R, Medarova Z, Farrar CT, Dai G, Moore A, Caravan P. Molecular Imaging of Fibrin in a Breast Cancer Xenograft Mouse Model. Invest Radiol, 2012, in press. Kavishwar A, Moore A. Molecular imaging of diabetic pancreas. Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry, 2012, in press. Wang P, Moore A. Molecular imaging of stem cell transplantation for neurodegenerative diseases. Curr Pharm Design, 2012, in press. Wang P, Yigit M, Ran C, Ross A, Wei L, Dai G, Medarova Z, Moore A. A theranostic siRNA nanoprobe protects pancreatic islet grafts from adoptively transferred immune rejection. Diabetes, 2012, doi: 10.2337/db12-0441. Wang P, Schuetz C, Ross A, Dai G, Markmann J, Moore A. In vivo MRI of immune rejection in pancreatic islet transplantation in a mouse model. Radiology 2012; in press. 2011Wang P, Yigit MV, Medarova Z, Wei L, Dai G, Schuetz C, Moore A. Combined siRNA therapy and in vivo MRI in islet transplantation, Diabetes, 2011, 60:565-571. PMCID: PMC3028356 Yigit M, Zhu L, Ifediba M, Zhang Y, Carr K, Moore A, Medarova, Z. Noninvasive MRI-SERS imaging in living mice using an innately bimodal nanomaterial, ACS Nano, 2011, 5:1056-1066. PMCID: PMC3078630 Ran C, Zhao W, Moir RD, Moore A. Non-conjugated small molecule FRET for differentiating monomers from high molecular weight amyloid beta species. PLoS ONE, 2011, 29;6(4):e19362. PMCID: PMC3084834 Medarova Z, Greiner DL, Ifediba M, Dai G, Bolotin E, Castillo G, Bogdanov A, Kumar M, Moore A. Imaging the pancreatic vasculature in diabetes models. Diab Metab Res Rev, 2011, 27: 767-772. Kavishwar A, Medarova Z, Moore A. Unique sphingomyelin patches are targets of a beta cell specific antibody, J Lipid Res, 2011, 52:1660-1671 (featured on the cover). PMCID: PMC3151686 Zuo Y, Lu H, Vaupel DB, Zhang Y, Chefer SI, Rea W, Moore A, Yang Y, Stein EA. Acute nicotine-induced tachyphylaxis is differentially manifest in the limbic system. Neuropsychopharmacology, 2011, 36:2498-2512. PMCID: PMC3194077 Wang P, Medarova Z, Moore A. Molecular Imaging: a promising tool to monitor islet transplantation, J Transplant, 2011 doi:10.1155/2011/202915 2010Kumar M, Medarova Z, Pantazopoulos P, Dai G, Moore A. Novel membrane permeable contrast agent for brain tumor detection by MRI. Magn Reson Med, 2010, 63:617-624. Tsai S, Shameli A, Yamanouchi J, Clemente-Casares X, Wang J, Serra P, Yang Y, Medarova Z, Moore A, Santamaria P. Reversal of Autoimmunity by Boosting Memory-like Autoregulatory T Cells. Immunity, 2010, 32:568-80 Ifediba MA, Medarova Z, Ng S, Yang J, Moore A. siRNA Delivery to CNS Cells using a Membrane Translocation Peptide, Bioconjugate Chem, 2010, 21:803-806. PMCID: PMC2874326 Ghosh SK, Kim P, Zhang, X, Yun SH, Moore A*, Lippard SJ*, Medarova Z*. A novel imaging approach for early detection of prostate cancer based on endogenous zinc sensing. Cancer Res, 2010, 79:6119-6127. * - senior authors. Kumar M, Yigit M, Dai G, Moore A, Medarova Z. Image-guided breast tumor therapy using a siRNA nanodrug. Cancer Res, 2010, 70:7553-7561. PMCID: PMC2948644 2009Medarova Z, Rashkovetsky L, Pantazopoulos P, Moore A. Multi-Parametric Monitoring of Tumor Response to Chemotherapy by Non-Invasive Imaging. Cancer Res, 2009, 69:1182-1189. PMCID: PMC2633414 Medarova Z, Moore A. MRI as a tool to monitor islet transplantation. Nat Rev Endocrinol, 2009, 5:444-452. Medarova Z, Moore A. Magnetic resonance imaging in diabetes: first results. Am J Roentgenol, 2009, 193:295-303. Moore A. Advances in beta-cell imaging, Eur J Radiol, 2009, 70:254-257. PMCID: PMC2680935 Medarova Z, Vallabhajosyula P, Tena A, Evgenov N, Pantazopoulos P, Tchipashvili V, Weir G, Sachs D, Moore A. In vivo imaging of autologous islet grafts in the liver and under the kidney capsule in non-human primates. Transplantation, 2009, 87(11):1659-1666. PMCID: PMC2746764 Ran C, Xu X, Raymond SB, Ferrara BJ, Neal K, Bacskai BJ, Medarova Z, Moore A. Design, synthesis, and testing of difluoroboron derivatized curcumins as near infrared probes for in vivo detection of amyloid-b deposits. J Am Chem Soc, 2009, 131:15257-15261. PMCID: PMC2784241 2008Medarova Z, Tsai S, Evgenov N, Santamaria P, Moore A. In vivo imaging of a diabetogenic CD8+ T cell response during type 1 diabetes progression, Magn Reson Med, 2008, 59:712-720. Erdogan S, Medarova Z, Roby A, Moore A, Torchilin V. Enhanced tumor MR imaging with gadolinium-loaded polychelating polymer-containing tumor- targeted liposomes, J Magn Reson Imaging, 2008, 27:574-580. Evgenov N, Pratt J, Pantazopoulos P, Moore A. Effects of Glucose Toxicity and Islet Purity on In Vivo MR Imaging of Transplanted Pancreatic Islets, Transplantation, 2008, 85:1091-1098. Medarova Z, Moore A. Non-invasive detection of transplanted pancreatic islets, Diabetes, Obes Metab, 2008, 10(s4):88-97. Medarova Z, Kumar, M, Ng, SW, Junzheng, Y, Barteneva N, Evgenov N, Petkova V, Moore A. Multifunctional magnetic nanocarriers for image-tagged siRNA delivery to intact pancreatic islets. Transplantation, 2008 86:1170-1177. PMCID: PMC2678246 Sakadzic S, Demirbas U, Mempel TR, Moore A, Ruvinskaya S, Boas DA, Sennaroglu A, Kaertner FX, Fujimoto JG. Multi-photon microscopy with a low-cost and highly efficient Cr:LiCAF laser, Optics Express 2008, 16:20848–20863. 2007Medarova Z, Pham W, Farrar C, Petkova V, Moore A. In vivo imaging of siRNA delivery and silencing in tumors. Nature Med, 2007, 13:372-377. Hillman BMC, Moore A. All-optical anatomical co-registration for molecular imaging of small animals using dynamic contrast. Nature Photonics, 2007, 1:526-530. PMCID: PMC2575379 Medarova Z, Castillo G, Dai G, Bolotin E, Bogdanov A, Moore A. Non-invasive magnetic resonance imaging of microvascular changes in Type 1 diabetes, Diabetes, 2007, 56:2677-2682. Ran C, Pantazopoulos P, Medarova Z, Moore A. Synthesis and testing of beta-cell specific streptozotocin-derived near infrared imaging probes, Angew Chem, 2007, 46-47:8998-9001. 2006Evgenov N, Medarova Z, Dai G, Bonner-Weir S, Moore A. In vivo imaging of islet transplantation. Nature Med, 2006, 12:144-148. Medarova Z, Pham W, Kim Y, Dai G, Moore A. In vivo imaging of tumor response Medarova Z, Evgenov N, Dai G, Bonner-Weir S, Moore A. In vivo multimodal imaging of transplanted pancreatic islets. Nature Prot, 2006, 1:428-434. Evgenov N, Medarova Z, Pratt J, Pantazopoulos P, Leyting S, Bonner-Weir S, Moore A. In vivo imaging of immune rejection in transplanted pancreatic islets. Diabetes, 2006, 55:2419-2428. Pham W, Pantazopoulos P, Moore A. Imaging farnesyl protein transferase using a topologically activated probe. J Am Chem Soc, 2006, 128:11736-11737. 2005Medarova Z, Bonner-Weir S, Lipes M, Moore A. Imaging b-cell death with a near-infrared probe. Diabetes, 2005, 54:1780-1788. Pham W, Medarova Z, Moore A. Synthesis and application of a water-soluble near-infrared dye for cancer detection using optical imaging.Bioconjugate Chem. 2005, 16: 735-740. Pham W, Zhao BQ, Lo E, Medarova Z, Rosen B, Moore A. Crossing the blood brain barrier: a potential application of myristoylated polyarginine for in vivo neuro-imaging. NeuroImage, 2005, 28:287-292. 2004Moore A, Medarova Z, Potthast A, Dai G. In vivo targeting of underglycosylated MUC-1 tumor antigen using a multi-modal imaging probe, Cancer Res, 2004, 64:1821-1827. Moore A, Grimm J, Han B, Santamaria P. Tracking the recruitment of diabetogenic CD8+ T cells to the pancreas in real time. Diabetes, 2004, 53:1459-1466. Medarova Z, Moore A. Imaging of pancreatic cancer: a promise for early diagnosis through targeted strategies. Cancer Ther, 2004, 2:329-344. Moore A, Medarova Z. Approaches for Imaging the Diabetic Pancreas: First Results. Curr Med Chem - Immun, Endoc & Metab Agents, 2004, 4:315-332. 2003Grimm J, Potthast A, Wunder A, Moore A. Magnetic resonance imaging of the pancreas and pancreatic tumors in a mouse orthotopic model of human cancer, Int J Cancer, 2003, 106:806-811. Moore A, Medarova Z. Targeting of uMUC-1 antigen expressed by human tumors for potential in vivo imaging: in vivo studies. Mol Imaging, 2003, 2:248-249 Medarova Z, Moore A. Targeting of uMUC-1 antigen expressed by human tumors for potential in vivo imaging: in vitro studies. Mol Imaging, 2003, 2:248. |