SPM8 Basics
   NEXT program: October 5-7, 2009
 
   There are no scheduled dates for this program in the future.
     Its content will be incorprated into the new workshop:
     "SPM8 for Basic and Clinical Investigators".

        Preprocessing, experimental design and statistical analysis with SPM8
        Quality assurance with various toolboxes
        Visualization, anatomical labeling with various toolboxes

 

        Curriculum Description and Educational Objectives
        Workshop Daily Schedule
        Registration Information
        Payment Information
        Accommodations (in new window)

 

CURRICULUM for SPM8 Basics Workshop

Introduction: SPM8 Basics is an intermediate-level, 3-day workshop is designed for investigators having familiarity with the fundamental principles of fMRI data acquisition and analysis.

Content: The workshop will focus on using SPM8 and its extensions for preprocessing, statistical modeling and visualization of data associated with a range of fMRI experimental designs. While the primary emphasis will involve using the core SPM8 programs for these purposes, there will also be extensive discussion of a variety of software tools that extend the power of SPM8. Some of these tools facilitate fMRI quality assurance through artifact detection and mitigation at various analysis stages. Other tools support a variety of data visualization schemes (including MRIcron, xjView, and FreeSurfer), and will be demonstrated interactively. We will review and demonstrate a range of strategies for labeling cortical and subcortical regions.

Anyone planning to use SPM as their primary statistical analysis and pre-processing software package should benefit from this program. Users of other software packages might want to wait until there are workshops for those packages. That said, SPM is the most widely used fMRI analysis package, and familiarity with it in some detail would be of general benefit to anyone in this field. Moreover, the quality control and visualization tools are applicable to most standard packages.

Participant Preparation: The workshop will involve demonstrations involving SPM8, its extensions and associated programs. It is necessary for participants have a means to work with this software during the program. Therefore, participants are expected to bring a laptop with MATLAB, SPM8 and MRIcron already installed. Instructions for downloading these programs and others will be included in the e-mail reply acknowledging your registration request. There may be a small number of laptops available for use (alone or shared) by those people who cannot bring one on their own. Please note that, although SPM itself is free and available for download from the web, its use requires an active MATLAB license (which is not free).

The primary faculty will normally be Tom Zeffiro, Susan Whitfield-Gabrieli and Robert Savoy. Tom and Susan have extensive experience with SPM, statistics and quality assurance in fMRI data analysis. Robert Savoy is the director of the fMRI Visiting Fellowship Program and the Multi-Modal Short Course at the Martinos Center.

Educational Objectives

  • Understand the basic organization of the SPM GUI
  • Understand the organization of the SPM "toolbox"
  • Be able to construct batch processing scripts for preprocessing and statistical modeling
  • Understand the basic fMRI data preprocessing steps
  • Be able to construct a preprocessing sequence including slice time correction, realignment, and spatial filtering
  • Understand the origins of the artifacts most commonly encountered in fMRI datasets
  • Be able to utilize explore an fMRI dataset for artifacts and effect repairs as needed
  • Understand the basic fMRI single subject experimental design types
  • Be able to implement statistical analysis procedures for the basic single subject fMRI designs
  • Understand the basic fMRI single group experimental design types
  • Be able to implement statistical analysis procedures for the basic single group fMRI designs
  • Understand the basic fMRI multiple group experimental design types
  • Be able to implement statistical analysis procedures for the basic multiple group fMRI designs
  • Understand the process of incorporation of covariates in fMRI experimental designs
  • Be able to construct and estimate statistical models involving covariates
  • Be able to utilize the RIC Talairach Daemon for region labeling
  • Be able to utilize the SPM Anatomy toolbox for region labeling
  • Be able to utilize the FreeSurfer for region labeling
  • Be able to use FreeSurfer to visualize statistical maps on the cortical surface
  • Be able to use MRIcron for data visualization, including volume rendering
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SCHEDULE for SPM8 Basics Workshop

 

Summary Schedule

Day 1 am:       Introduction to SPM8
Day 1 pm:       Preprocessing

Day 2 am:       Artifact prevention, detection and mitigation
Day 2 pm:       First-level experimental design and analysis

Day 3 am:       Second-level design and analysis; anatomical labeling
Day 3 pm:       Various second level designs; batch processing

Lunch each day is scheduled for 90 minutes. During the last 45 minutes of that period, there will be brief reviews or introductions to topics for less experienced users.

 

Detailed Schedule

Day 1

9AM-12PM      Introduction to SPM8
      * Workshop overview - Zeffiro/Savoy
      * New features in SPM8 - Zeffiro
      * The SPM8 interface - Zeffiro
      * Introduction to batch processing - Zeffiro
      * Structural processing - Zeffiro

12PM-1:30PM LUNCH
       12:15-1:30 Basic fMRI Data Acquisition, Experimental Design, and Analysis - Savoy

1:30PM-4:30PM      Preprocessing
      * Preprocessing overview and background - Zeffiro
      * Slice time correction - Zeffiro
      * Realignment - Zeffiro
      * Unwarping - Zeffiro
      * Spatial filtering - Zeffiro
      * Spatial normalization - Zeffiro

4:30-5:30PM Special topics and questions - Savoy/Zeffiro

 

Day 2

9AM-12PM      Artifact prevention, detection and mitigation
      * Sources of artifacts in EPI - Zeffiro
      * Detection and repair of EPI artifacts - Whitfield-Gabrieli
      * ART demonstration - Whitfield-Gabrieli
      * Visualization with SPM8, FreeSurfer, MRIcron and xjview - Zeffiro

12:30PM-1:30PM LUNCH
       12:15-1:30 Lightning Review of GLM, Data Analysis - Savoy

1PM-4PM      First-level experimental design and analysis
      * Experimental design in fMRI - Savoy
      * Statistical modeling in SPM8: summary statistics - Zeffiro
      * First-level fMRI designs overview - Zeffiro
      * First-level fMRI designs demonstration - Zeffiro

4-5PM Special topics and questions - Savoy /Zeffiro

 

Day 3

9AM-12PM      Second-level design and analysis
      * Second-level fMRI designs overview - Zeffiro
      * Second-level fMRI designs demonstration - Zeffiro
      * Anatomical localization and labeling - Zeffiro
      * Anatomical localization demonstration - Zeffiro

12PM-1:30PM LUNCH
       12:15-1:30 General Questions - Savoy

1:30PM-4:30PM      Group analysis and batch processing
      * Single group second-level designs - Zeffiro
      * Multi-group second-level designs - Zeffiro
      * Covariates in second-level designs - Zeffiro
      * Batch processing revisited - Zeffiro
      * Batch processing demonstration - Zeffiro

4:30-5:30PM Special topics and questions - Savoy/Zeffiro

 

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REGISTRATION information for SPM8 Basics Workshops

To register: Please send an e-mail to Robert Savoy at savoy@nmr.mgh.harvard.edu.
NOTE: Please include the word SPM8_04 in your subject line for the Oct 5-7 Workshop.

 

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PAYMENT Information for SPM8 Basics Workshops

Fees:
$750 For standard registration
$450 For students, Martinos Center members, and Current Participants in an ongoing fMRIVFP

 

Payment can be made by credit card or check
Information for making payments will be sent with an acknowledging e-mail when you register for the program. Registration is accomplished by sending an e-mail to Robert Savoy: savoy@nmr.mgh.harvard.edu

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