Functional MRI Visiting Fellowship:
            A Five Day Intensive Introduction

    Program Dates:   March 25-29, 2013         Program Code:   2013Mar25
 
    Program Dates:   Sep 30 - Oct 4, 2013       Program Code:   2013Sep30
 

SHORT COURSE IN FUNCTIONAL MAGNETIC RESONANCE IMAGING

The pioneering work of the Martinos Center has elicited an explosion of research in functional brain imaging. While it has been known for almost 100 years that neural activity causes localized changes in blood flow, and has been more recently demonstrated that neural activity causes localized changes in blood oxygenation, the tools for measuring these signals have historically been highly invasive in animals, and moderately invasive in humans. The seminal work of an extraordinary team of physicists, radiologists, and neuroscientists at the Martinos Center, demonstrating that these changes and blood flow and blood oxygenation can be detected by the non-invasive technology of MRI, has led to a dramatic increase in functional brain imaging work with humans. Because this non-invasive technique permits many repetitions of experimental procedures on a single subject, it is rapidly becoming the method of choice for neuroscience research in functional brain mapping.

The purpose of the present course is to provide a serious introduction to this field. It is primarily intended for people new to the field, though some experienced scientists have found the program useful.

CURRICULUM

Students will receive a firm grounding in the fundamentals of fMRI. This will include the basic physics of MR imaging, the biology and biophysics of the hemodynamic responses to neural activity, data analysis (including both exploratory and statistical analyses), stimulus presentation and response recording in the context of high magnetic fields and electromagnetic pulses, and the design of perceptual and cognitive experiments. Some advanced topics (especially related to issues of connectivity) have been added.

A special emphasis of the course will be the design, implementation, and execution of perceptual and/or cognitive experiments by the participants. Participants will break into small groups to design their own fMRI experiments. Barring unforeseen problems, some of these experiments will be executed, and the resulting data analyzed, on the final day of the course.

The core faculty is drawn from the staff of the Athinoula A. Martinos Center (of the Massachusetts General Hospital and Massachusetts Institute of Technology) and affiliated faculty from Harvard University, Boston University, McLean Hospital and other institutions.

SCHEDULE