Hesheng Liu is an Assistant
Professor at Harvard Medical School and the Martinos Center
for Biomedical Imaging, Massachusetts General Hospital. He also
serves as the Director of The Laboratory for the Study of the
Brain Basis of Individual Differences at MGH.His research seeks
to understand what makes individual brain's distinct. Although
human brains share common structural and functional properties,
considerable differences exist between people. A major goal of his
work is to improve surgical planning for epilepsy and brain tumor
patients, which requires precise mapping of the brain systems in
individual patients. Another goal is to find individual differences
that mark psychiatric disorders such as schizophrenia. Using modern
imaging and computational technologies, he aims to develop reliable
signatures of psychiatric illness that can provide increased
statistical power for investigating genetic associations and
determining risk of illness. To facilitate these investigations,
he has built a platform to merge information within an individual
from multiple imaging modalities including anatomical and functional
MRI, MEG/EEG, and intracranial ECoG.
Hesheng's [website]
Mueller, S., Wang, D., Fox, M.D.,
Sepulcre, J., Sabuncu, M.R., Shafee, R., Lu, J., &
Liu,
H.. (in press) Individual
variability in functional connectivity architecture of the human
brain. Neuron.
Wang, D., Buckner, R.L, & Liu,
H. (2013) Cerebellar asymmetry
and its relation to cerebral asymmetry estimated by intrinsic functional
connectivity. Journal of Neurophysiology, 109(1):46-57.
[medline abstract]
Lu, J.*, Liu,
H.*, Zhang, M., Wang, D.,
Cao, Y., Ma, Q., Rong, D., Wang, X., Buckner, R.L., & Li, K. (2011) Focal pontine
lesions provide evidence that intrinsic functional connectivity reflects
polysynaptic anatomical pathways. Journal of Neuroscience, 31(42):15065-71.
[medline abstract]
Liu,
H., Stufflebeam, S.M., Sepulcre,
J., Hedden, T., & Buckner, R.L. (2009) Evidence from intrinsic activity
that asymmetry of the human brain is controlled by multiple factors.
Proceedings of the National Academy of Sciences, U.S.A., 106(48):20499-503. [medline abstract]
Liu,
H., Agam, Y., Madsen, J.R.,
Krieman, G. (2009) Timing, timing, timing: Fast decoding of object
information from intracranial field potentials in human visual cortex.
Neuron, 62(2):281-90. [medline abstract]
