squiqally

My main research interest is in understanding the role of dopamine in human cognition and disease. I am using both PET and fMRI to explore whether changes in the integrity of the dopamine system across the adult lifespan contribute to age-related declines in cognitive functions. My current research project investigates whether dopamine-related changes in cognition and functional connectivity in older adults are dissociable from other age-related cascades, such as those associated with amyloid accumulation and white matter changes. Recently, I have also developed an interest in pharmacological MRI as a tool for studying the effects of pharmacological manipulations of the dopamine system on brain and behavior.

squiqally

Rieckmann, A., Karlsson, S., Fischer, H., & Bäckman, L. (2012) Increased bilateral frontal connectivity during working memory in young adults under the influence of dopamine D1 receptor antagonist. Journal of Neuroscience, 32, 17067-17072. [medline abstract]

Rieckmann, A., Karlsson, S., Fischer, H., & Bäckman, L. (2011) Caudate dopamine D1 receptor density is associated with individual differences in frontoparietal connectivity during working memory. Journal of Neuroscience, 31, 14284-14290. [medline abstract]

Rieckmann, A., Karlsson, S., Karlsson, P., Brehmer, Y., Fischer, H., Farde, H., Nyberg, L., & Bäckman, L. (2011) Dopamine D1 receptor associations within and between dopaminergic pathways in younger and elderly adults: links to cognitive performance. Cerebral cortex, 21, 2023-2032. [medline abstract]

Rieckmann, A., Fischer, H., & Bäckman, L. (2010) Activation in striatum and medial temporal lobe during sequence learning in younger and older adults: relations to performance. NeuroImage, 50, 13030-1312. [medline abstract]

Rieckmann, A., & Bäckman, L. (2009) Implicit learning in aging: extant patterns and new directions. Neuropsychology Review, 19, 490-503. [medline abstract]