Topics: Normal and pathological human brain aging,
Alzheimer's disease, mild cognitive impairment, dementia, large scale neuronal
networks, white matter hyperintensities, in-vivo amyloid imaging.
Tools: Magnetic resonance imaging (MRI), resting-state fMRI, task-based fMRI,
functional connectivity MRI, diffusion imaging, positron emission tomography (PET),
longitudinal study design (i.e. multiple measures over time), linear mixed models
for handling more than two measures over time and missing data.
Google Scholar citations [here]
Selection of Publications:
Van Dijk,
K.R.A., Sperling,
R.A. (2011) Defaulting on the default network: Increased
risk for dementia, Neurology; 76(6): 498-500.
[full text]
Van
Dijk, K.R.A., Sabuncu, M.R., & Buckner, R.L.
(2012) The influence of head motion on intrinsic functional connectivity MRI.
NeuroImage, 59(1):431-8
[abstract] (send me an e-mail if you would like a copy)
Hedden, T., Van
Dijk, K.R.A., Shire, E.H.,
Sperling, R.A., Johnson, K.A., & Buckner, R.L. (2011) Failure to modulate
attentional control in advanced aging linked to white matter pathology.
Cerebral Cortex, 22(5):1038-1051.
[full text]
Drzezga, A., Becker, A.J., Van Dijk, K.R.A., Sreenivasan, A., Talukdar, T.,
Sullivan, T., Schultz, A.P., Sepulcre, J., Putcha, D.,
Greve, D., Johnson, K.A., Sperling, R. (2011) Neuronal
dysfunction and disconnection of cortical hubs in
non-demented subjects with elevated amyloid-burden. Brain, 134(6): 1635-46.
[full text]
Van Dijk,
K.R.A, Hedden, T.,
Venkataraman, A., Evans, K.C., Lazar, S.W., Buckner, R.L.
(2010) Intrinsic functional connectivity as a tool for
human connectomics: theory, properties, and optimization,
Journal of Neurophysiology; 103: 297-321.
[full text]
Hedden, T., Van
Dijk, K.R.A.,
Becker, A.J., Mehta, A., Sperling, R.A., Johnson, K.A.,
Buckner, R.L. (2009) Disruption of functional connectivity
in clinically normal older adults harboring amyloid burden,
Journal of Neuroscience; 29(40): 12686-12694.
[full text]
Van Dijk, K.R.A.,
Van Gerven, P.W.M., Van Boxtel, M.P.J., Van der Elst, W.,
Jolles, J. (2008) No protective effects of education during
normal cognitive aging: results from the 6-year follow-up
of the Maastricht Aging Study (MAAS), Psychology and Aging;
23 (1): 119-130. [full text]
Van Breukelen, G.J.P., Van
Dijk, K.R.A. (2007) Letter to the Editor:
Use of covariates in randomized controlled trials. Journal of the International
Neurophsychological Society, 13(5):903-4.
[full text]
