J Comp Neurol. 2013 Jul 25. doi: 10.1002/cne.23432. [Epub ahead of print]

Medial temporal cortices in ex vivo MRI

Augustinack JC, van der Kouwe AJ, Fischl B.

Abstract

This review focuses on the ex vivo MRI modeling of medial temporal cortices and associated structures, the entorhinal verrucae and the perforant pathway. Typical in vivo MRI has limited resolution due to constraints on scan times and does not show laminae in the medial temporal lobe. Recent studies using ex vivo MRI have demonstrated lamina in the entorhinal, perirhinal and hippocampal cortices. These studies have enabled probabilistic brain mapping that is based on the ex vivo MRI contrast, validated to histology and subsequently mapped onto an in vivo spherically warped surface model. Probabilistic maps are applicable to other in vivo studies. J. Comp. Neurol., 2013. (c) 2013 Wiley Periodicals, Inc.

PMID: 23881818