Lisa Shin, PhD

Professional Information


Professor, Tufts University


PhD Psychology, Harvard University, 1997

Affiliated Faculty


Mailing Address

Psychiatric Neuroscience, Building 149-Second Floor, 13th Street, Charlestown, MA 02129

General Contact Information



My research involves examining brain function and cognitive processing in patients with anxiety disorders, especially posttraumatic stress disorder (PTSD). Specifically, I use positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) to study brain function while patients perform attention and memory tasks in the scanner. The goal of this research is to determine whether brain structures such as the amygdala, medial prefrontal cortex, and hippocampus function normally in patients with PTSD. Evidence thus far suggests that in PTSD, the amygdala is hyperresponsive and medial prefrontal cortex is hyporesponsive to threat-related stimuli. We are currently conducting studies to determine (1) whether these biomarkers are familial risk factors or acquired signs of PTSD and (2) whether functional neuroimaging measures can help predict response to treatment. My research interests also include studying the neural mechanisms underlying the processing of emotional information (e.g., facial expressions, emotional words and pictures) in healthy individuals.