Anastasia Yendiki, PhD

Professional Information

Experience: 

Assistant Professor in Radiology, Harvard Medical School
Assistant Physicist, Massachusetts General Hospital

Education: 

PhD Electrical Engineering: Systems, The University of Michigan, Ann Arbor, MI, 2005

Position: 
Martinos Faculty

Contact

Mailing Address

Building 149, Room 2301
149 13th St.
Charlestown, MA 02129 USA

General Contact Information

Phone: 
617-726-9434
Location: 
CNY149-2246

Biosketch


My research focuses on methods for mapping the circuitry of the human brain in health and disease. I have developed TRACULA (TRActs Constrained By UnderLying Anatomy), a software tool for reconstructing white-matter pathways from diffusion MRI data based on prior anatomical knowledge. Instead of enforcing hard constraints on the trajectories of the pathways, this approach includes a detailed probabilistic model of the anatomical regions that a pathway traverses at every point along its trajectory. This allows the same pathway to be reconstructed automatically in a novel subject, even if its shape and integrity differs from those of the subjects that were used to train the algorithm. Some of my current research projects include: validation and optimization of diffusion MRI; development of analysis methods for longitudinal diffusion MRI data; and applications in traumatic brain injury and Huntington's disease.