Hesheng Liu, PhD

Professional Information


Associate Professor of Radiology, Harvard Medical School
Assistant in Neuroscience, Massachusetts General Hospital


PhD Biomedical Engineering, Tsinghua University, China,

Martinos Faculty


Mailing Address

Building 149, Room 2301
13th Street
Charlestown,, MA 02129 USA

General Contact Information



Our research focused on multi-modal brain imaging aimed at understanding individual differences. A major goal of our work is to improve surgical planning for epilepsy and brain tumor patients. Another goal is to develop imaging phenotypes that will help us identify genetic underpinnings of some psychiatric diseases such as schizophrenia.

Selected Publications:

Tang, W.*, Liu H*, Douw, L., Kramer, M.A., Eden, U.T., Hmlinen, M.S. and Stufflebeam, S.M. Dynamic connectivity modulates local activity in the core regions of the default-mode network. Proc Natl Acad Sci U S A. 114(36), pp.9713-9718. 2017. * (Corresponding Authors).

Wang D, Buckner RL, Fox MD, Holt DJ, Holmes AJ, Mueller S, Langs G, Pan R, Qian T, Li K, Baker J, Stufflebeam SM, Wang K, Wang X, Hong B, Liu H. Parcellating Cortical Functional Networks in Individuals. Nat. Neurosci. 2015;18: 1853-60.

Langs G, Wang D, Golland P, Mueller S, Pan R, Sabuncu MR, Sun W, Li K, Liu H.Identifying Shared Brain Networks in Individuals by Decoupling Functional and Anatomical Variability. Cereb Cortex. 2015; bhv189

Mueller S, Wang D, Pan R, Holt D, Liu H. Abnormalities in Hemispheric Specialization of Caudate Nucleus Connectivity in Schizophrenia. JAMA Psychiatry 2015; 72(6):552-60.

 Wang D, Buckner RL, Liu H. Functional Specialization in the Human Brain Estimated By Intrinsic Hemispheric Interaction. J Neurosci. 2014; 34(37): 12341-12352.

 Zeng L, Wang D, Fox MD, Sabuncu M, Hu D, Ge M, Buckner RL, Liu H. A Neurobiological Basis of Head Motion in Brain Imaging. Proc Natl Acad Sci U S A. 2014; 111(16): 6058-6062.

 Mueller S, Wang D, Fox MD, Yeo BTT, Sepulcre J, Sabuncu MR, Shafee R, Lu J, Liu H. Individual Variability in Functional Connectivity Architecture of the Human Brain. Neuron 2013; 77(3): 586-595.

 Lu J*, Liu H*, Zhang M, Wang D, Cao Y, Ma Q, Rong D, Wang X, Buckner RL, Li K. Focal pontine lesions provide evidence that intrinsic functional connectivity reflects polysynaptic anatomical pathways. J Neurosci. 2011; 31(42):15065-71.

 Liu H, Stufflebeam SM, Sepulcre J, Hedden T, Buckner RL. Evidence from intrinsic activity that asymmetry of the human brain is controlled by multiple factors. Proc Natl Acad Sci U S A. 2009 Dec 1; 106(48):20499-503.

 Liu H, Agam Y, Madsen JR, Kreiman G. Timing, timing, timing: fast decoding of object information from intracranial field potentials in human visual cortex. Neuron. 2009 Apr 30; 62(2):281-90.