Publications


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 [1] Characterization of the active site of p21 ras by electron spin-echo envelope modulation spectroscopy with selective labeling; Comparison between GDP and GTP forms. C.J. Halkides, C.T. Farrar, R.G. Larsen, A.G. Redfield, and D.J. Singel.  Biochemistry 33(13), 4019-4035 (1994).

 

[2] Characterization of optical centers in Mn:Ba3(VO4)2 by spin-echo EPR spectroscopy.  M.H. Whitmore, C.T. Farrar, D.J. Singel, B. Buysee, J. Coremans, and J. Schmidt. OSA Proc. on Adv. Solid-State Lasers 20, 219-221 (1994).

 

[3] Electronic structure of the tris-(1,3-diphenyltriazenido)aluminum radical anion: A theoretical and experimental  EPR and ESEEM study.  C.T. Farrar, J.T. Leman, S.C. Larsen, J. Braddock-Wilking, D.J. Singel, and A.R. Barron.  J. Am. Chem. Soc. 117, 1746-1753 (1995).

 

[4] Radical anion complexes of tris-(1,3-diphenyltriazenido)aluminum. J. Braddock-Wilking, J.T. Leman, C.T. Farrar, S.C. Larsen, D.J. Singel, and A.R. Barron.  J. Am. Chem. Soc. 117, 1736-1736-1745 (1995).

 

[5] The active site of p21 ras: Conformational changes induced by the binding of nucleotides.  C.J. Halkides, C.T. Farrar, A.G. Redfield, and D.J. Singel.  Biolog. Str. & Dynamics, Vol. 1, R.H Sarma & M.H. Sarma, Eds., Adenine Press, Guilderland, New York (1995).

 

[6] High frequency (139.5 GHz) electron paramagnetic resonance spectroscopy of the GTP form of p21 ras with selective 17O-labeling of threonine.  C.J. Halkides, B.F. Bellew, G.J. Gerfen, C.T. Farrar, P.H. Carter, B. Ruoll, D.A. Evans, R.G. Griffin, and D.J. Singel.   Biochemistry 35(37), 12194-12200 (1996).

 

[7] Electronic structure of the YD tyrosyl radical in photosystem II: A high frequency EPR spectroscopic and density functional theoretical study.  C. T. Farrar, G. J. Gerfen, R. G. Griffin, Dee Ann Force, and R. David Britt. J. Phys. Chem. B 101, 6634-6641 (1997).

 

[8] The frozen solution structure of p21 ras determined by ESEEM spectroscopy reveals weak coordination of Thr35 to the active site metal ion. C.T. Farrar, C.J. Halkides, and D.J. Singel.  Structure 5(8), 1055-1066 (1997).

 

[9] Characterization of a substrate derived radical detected during the inactivation of ribonucleotide reductase from Escherichia coli by 2'-fluoromethylene-2'-deoxycytidine 5'-diphosphate.  G.J. Gerfen, W.A. van der Donk, G. Yu, J.R. McCarthy, E.T. Jarvi, D.P. Matthews, C.T. Farrar, R.G. Griffin, and J. Stubbe.  J. Am. Chem. Soc. 120(16), 3823-3835 (1998).

 

[10] The effects of cryoprotectants on the structure and activity of p21 ras: Implications for electron spin-echo envelope modulation spectroscopy.  C.J. Halkides, C.T. Farrar, and D.J. Singel.  J. Magn. Reson. 134, 142-153 (1998).

 

[11] The use of a 250 GHz gyrotron in a DNP/EPR spectrometer. K.E. Kreischer, C.T. Farrar, R.G. Griffin, and R.J. Temkin, Proc. 23rd Intl. Conf. Infrared and Millimeter Waves, 357-358 (1998).

 

[12] Pulsed electron nuclear double resonance (ENDOR) at 140 GHz.  M.L. Bennati, C.T. Farrar, J.A. Bryant, S.J. Inati, V. Weis, G.J. Gerfen, P. Riggs-Gelasco, J. Stubbe, and R.G. Griffin.  J. Magn. Reson. 138, 232-243 (1999).

 

[13] High frequency dynamic nuclear polarization in the nuclear rotating frame.  C.T. Farrar, D.A. Hall, G.J. Gerfen, M. Rosay, and R.G. Griffin. J. Magn. Reson. 144, 134-141 (2000).

 

[14] Structural changes induced in p21Ras upon GAP-334 complexation as probed by ESEEM spectroscopy and molecular dynamics simulation. C.T. Farrar, J. Ma, D.J. Singel, and C.J. Halkides.  Structure 8(12), 1279-1287 (2000).

 

[15] Electron spin resonance of TOAC labeled peptides: Folding transitions and high frequency spectroscopy.  J.C. McNulty, J. L. Silapie, M. Carnevali, C.T. Farrar, R.G. Griffin, F. Formaggio, M. Crisma, C. Toniolo, and G.L. Millhauser.  Biopolymers (Peptide Science) 55, 479-485 (2000).

 

[16] Mechanism of dynamic nuclear polarization at high magnetic fields. C.T. Farrar, D.A. Hall, G.J. Gerfen, S.J. Inati, and R.G. Griffin. J. Chem. Phys. 114, 4922-4933 (2001).

 

[17] Dynamic nuclear polarization at 9 Tesla using a novel 250 GHz gyrotron microwave source. V.S. Bajaj, C.T. Farrar, M.K. Hornstein, I. Mastovsky, J. Vieregg, J. Bryant, B. Elena, K.E. Kreischer, R.J. Temkin, and R.G. Griffin.  J. Magn. Reson. 160, 85-90 (2003).

 

[18] Cylindrical meanderline radiofrequency coil for intravascular magnetic resonance studies of atherosclerotic plaque. C.T. Farrar, V.J. Wedeen, and J.L. Ackerman. Magn. Reson. Med. 53, 226-230 (2005).

 

[19] In vivo imaging of siRNA delivery and silencing in tumors. Z. Medarova, W. Pham, C.T. Farrar, V. Petkova, A. Moore. Nature Med. 13, 372-377 (2007).

 

[20] Effects of a nucleoside reverse transcriptase inhibitor, stavudine, on glucose disposal and mitochondrial function in muscle of healthy adults. A. Fleischman, S. Johnsen, D.M. Systrom, M. Hrovat, C.T.Farrar, W. Frontera, K. Fitch, B.J. Thomas, M. Torrian, H.C.F. Cote, S.K. Grinspoon. Am. J. Physiol. Endriconol. Metab. 58, E1666-E1673 (2007).

 

[21] MR contrast probes that trace gene transcripts for cerebral ischemia in live animals. C.H. Liu, S. Huang, J. Cui, Y.R. Kim, C.T. Farrar, M.A. Moskowitz, B.R. Rosen, P.K. Liu. FASEB 21, 3004-3015 (2007).

 

[22] Impact of field strength and iron-oxide nanoparticle concentration on the linearity and diagnostic accuracy of off-resonance imaging. C.T. Farrar, G. Dai, M. Novikov, A. Rosenzweig, R. Weissleder, B.R. Rosen, and D.E. Sosnovik. NMR Biomed. (published online, October 2007).

 

[23] Corrections for artifacts in chemical exchange saturation transfer (CEST) imaging from B0 and B1 field errors. P.Z. Sun, C.T. Farrar, and A.G. Sorensen. Magn. Reson. Med. 58, 12017-1215 (2007).

 

[24] Influence of molecular parameters and increasing magnetic field strength on relaxivity of T1 contrast agents. P. Caravan, C.T. Farrar, L. Frullano, and R. Uppal. Contrast Media Molec Imag 4, 89-100 (2009).

 

[24] Edema control by cediranib, a vascular endothelial growth factor receptor-targeted kinase inhibitor, prolongs survival despite persistent brain tumor growth in mice. W.S. Kamoun, C.D. Ley, C.T. Farrar, A.M. Duyverman, J. Lahdenranta, D.A. Lacorre, T.T. Batchelor, E. di Tomaso, D.G. Duda, L.L. Munn, D. Fukumura, A.G. Sorensen, and R.K. Jain. J. Clin. Oncol. 27, 2542-2552 (2009).

 

[25] Target specific contrast agents for magnetic resonance microscopy. M.L. Blackwell, C.T. Farrar, B. Fischl, B.R. Rosen. NeuroImage 46, 382-393 (2009).