Curriculum Vitae

Richard Hoge
Mass. General Hospital NMR Center
Building 149
13th Street
Charlestown, MA
02129 U.S.A.
(617) 726-8790
rhoge@nmr.mgh.harvard.edu

Education

McGill University Dept. of Biomedical Engineering (Montreal, Canada)
I completed my Ph.D. in January 1999 under the supervision of Dr. G.B. Pike.
I obtained an M.Sc. degree in Medical Physics with the same supervisor in 1996.

Carleton University (Ottawa, Canada)
I obtained a B.Sc. with honours in Physics in 1989.

Research Activities

Massachusetts General Hostpital NMR Center/Harvard University Dept. of Radiology
Since January, 1999 I have been working as a post-doctoral fellow at the MGH NMR Center with Dr. Bruce Rosen. I have been extending quantitative fMRI technology in order to study the mechanisms of BOLD contrast, apply CMRO2 imaging methods to overcome problems of global masking in dyspnea studies, and understand the pathophysiology of Alzheimer's and Parkinson's disease.

Montreal Neurological Institute, McGill University: As a Master's and Ph.D. student, I investigated physiological and biophysical issues relevant to functional magnetic resonance brain imaging (fMRI).

Defence Research Establishment of Ottawa, University of Ottawa: As a research assistant in the University of Ottawa Psychology Department, I helped conduct EEG studies on the effects of hypercapnia and hypothermia.

Herzberg Institute of Astrophysics, National Research Council: As a summer student, I worked with Dr. D. Wallis studying magnetic wave phenomena in the Earth's ionosphere.

Teaching

I worked as a teaching assistant in the Carleton University Physics Department. The position involved teaching and supervision of first year undergraduates in the general physics laboratory, and second year students in a lab course on electricity and magnetism.

Computer/technical experience

• MRI pulse sequence programming for Siemens (Pargen/SDE), Philips (GOALC) environments

• general programming in perl (with CGI and Tk extensions), C

• OpenGL graphics programming (including GLstim, an OpenGL-based stimulus presentation program for fMRI)

• porting applications between Linux, Sun/Solaris, SGI/IRIX

• DICOM/file format conversion (implemented a data archiving system, based on Peter Neelin's ACR-NEMA libraries, for Siemens MRI systems at Mass. General Hospital NMR Center)

• Matlab applications development (signal/image processing, MRI simulation)

• Linux system adminstration

Other Employment

From 1990 to 1993 I worked full time as police officer with the RCMP (the federal police agency in Canada). Duties included narcotics, counterfeit, and organized crime investigations as well as operations against computer-related crimes. I also did rotations in Executive and Diplomatic Protection (EDPS), Tactical Troop, and Customs.

Scholarships and Awards

• the I.I. Rabi Award in Basic Science, International Society for Magnetic Resonance in Medicine Young Investigator Competition, 1999.

• McGill University Dean's Honour List (Ph.D.), 1999.

• Canadian National Sciences and Engineering Research Council (NSERC)
  Postdoctoral Fellowship, 1998

• Le Fonds pour la Formation de Chercheurs et l'Aide à la Recherche (Fonds FCAR)
  Doctoral Research Scholarship, 1997

• McGill University Dean's Honour List (M.Sc.), 1996.

Research Grants

• Whitaker Foundation Biomedical Engineering Research Grant, 1998
  (co-investigator)

• NIH RO1 (Magnetic Resonance Imaging of CMRO2), 2000
  (co-investigator)

Publications

First-author publications:

• Richard D. Hoge, Jeff Atkinson, Brad Gill, Gérard R. Crelier, Sean Marrett, and G. Bruce Pike. Investigation of BOLD Signal Dependence on CBF and CMRO2: the Deoxyhemoglobin Dilution Model. Magnetic Resonance in Medicine, 42(5):849-63, Nov 1999.

• Richard D. Hoge, Jeff Atkinson, Brad Gill, Gérard R. Crelier, Sean Marrett, and G. Bruce Pike. Linear Coupling Between Cerebral Blood Flow and Oxygen Consumption in Activated Human Cortex. Proc. Natl. Acad. Sci. USA, 96(16):9403-8, Aug 3 1999.

• Richard D. Hoge, Jeff Atkinson, Brad Gill, Gérard R. Crelier, Sean Marrett, and G. Bruce Pike. Stimulus-Dependent BOLD and Perfusion Dynamics in Human V1. Neuroimage, 9:573-585, 1999.

• Richard D. Hoge, Remi K.S. Kwan, and G. Bruce Pike. Density compensation functions for spiral MRI. Magnetic Resonance in Medicine, 38:117-128, 1997.

Co-authored publications:

• H. Reddy, S. Narayanan, P.M. Matthews, R.D. Hoge, G.B. Pike, P. Duquette, J. Antel, and D.L. Arnold. Relating axonal injury to functional recovery in MS. Neurology, 54(1):236-9, Jan 2000.

• Gérard R. Crelier, Richard D. Hoge, Patrice Munger, and G. Bruce Pike. Perfusion-based functional magnetic resonance imaging with single-shot RARE and GRASE acquisitions. Magnetic Resonance in Medicine, 41(1):132-6, 1999.

• Colin J. Holmes, Richard Hoge, Louis Collins, Roger Woods, Arthur W. Toga, and Alan C. Evans. Enhancement of magnetic resonance images using registration for signal averaging. Journal of Computer Assisted Tomography, 22(2):324-333, 1998.

Book chapters:

• G.B. Pike and R.D. Hoge. Functional Magnetic Resonance Imaging, in The Imaging of Pain, IASP Press (in press).

• R.D. Hoge and G.B. Pike. Quantitative Measurement using fMRI, in Functional Magnetic Imaging of the Brain: Methods for Neuroscience, Oxford University Press (in press).

Theses:

• R.D. Hoge. Enhancement of volume coverage and temporal resolution for functional magnetic resonance brain imaging. M.Sc. Thesis, McGill University, Montreal, 1996.

• R.D. Hoge. Magnetic Resonance Imaging of Cerebral Oxygen Consumption and Perfusion. Ph.D. Thesis, McGill University, Montreal, 1999.