This website is dedicated to support and disseminate the empirical data employed in a large-scale experiment, where clinical variables are predicted from structural brain MRI scans. Initial results and further details can be found in the following article:

“Clinical prediction from structural brain MRI scans: A large-scale empirical study” by Mert R. Sabuncu and Ender Konukoglu, Neuroinformatics, accepted.

The data in this initial study are compiled from six publicly available datasets:

1)    The Alzheimer’s Disease Neuroimaging Initiative, or ADNI (www.adni-info.org) (Jack et al., 2008),

2)    The Open-Access Series of Imaging Studies (OASIS, oasis-brains.org) (Marcus et al., 2007),

3)    The Autism Brain Imaging Data Exchange (ABIDE, tinyurl.com/fcon1000-abide) (Nielsen et al., 2013),

4)    The Attention Deficit Hyperactivity Disorder (ADHD) sample from the ADHD-200 Consortium  (tinyurl.com/fcon1000-adhd) (Milham et al., 2012),

5)    The Center for Biomedical Research Excellence (COBRE) schizophrenia sample (tinyurl.com/fcon1000-cobre) (Mayer et al., 2012), and

6)    The MIND Clinical Imaging Consortium (MCIC, coins.mrn.org) schizophrenia sample (Gollub et al., 2013).

 

REFERENCES

Gollub, R.L., Shoemaker, J.M., King, M.D., White, T., Ehrlich, S., Sponheim, S.R., Clark, V.P., Turner, J.A., Mueller, B.A., Magnotta, V., 2013. The MCIC Collection: A Shared Repository of Multi-Modal, Multi-Site Brain Image Data from a Clinical Investigation of Schizophrenia. Neuroinformatics, 1-22.

Jack, C.R., Bernstein, M.A., Fox, N.C., Thompson, P., Alexander, G., Harvey, D., Borowski, B., Britson, P.J., L Whitwell, J., Ward, C., 2008. The Alzheimer's disease neuroimaging initiative (ADNI): MRI methods. Journal of Magnetic Resonance Imaging 27, 685-691.

Marcus, D.S., Wang, T.H., Parker, J., Csernansky, J.G., Morris, J.C., Buckner, R.L., 2007. Open Access Series of Imaging Studies (OASIS): cross-sectional MRI data in young, middle aged, nondemented, and demented older adults. Journal of Cognitive Neuroscience 19, 1498-1507.

Mayer, A.R., Ruhl, D., Merideth, F., Ling, J., Hanlon, F.M., Bustillo, J., Cañive, J., 2012. Functional imaging of the hemodynamic sensory gating response in schizophrenia. Human brain mapping.

Milham, M.P., Fair, D., Mennes, M., Mostofsky, S.H., 2012. The ADHD-200 consortium: a model to advance the translational potential of neuroimaging in clinical neuroscience. Frontiers in systems neuroscience 6, 62.

Nielsen, J.A., Zielinski, B.A., Fletcher, P.T., Alexander, A.L., Lange, N., Bigler, E.D., Lainhart, J.E., Anderson, J.S., 2013. Multisite functional connectivity MRI classification of autism: ABIDE results. Frontiers in human neuroscience 7.