""" ======================================================= Permutation F-test on sensor data with 1D cluster level ======================================================= One tests if the evoked response is significantly different between conditions. Multiple comparison problem is addressed with cluster level permutation test. """ # Authors: Alexandre Gramfort # # License: BSD (3-clause) import matplotlib.pyplot as plt import mne from mne import io from mne.stats import permutation_cluster_test from mne.datasets import sample print(__doc__) ############################################################################### # Set parameters data_path = sample.data_path() raw_fname = data_path + '/MEG/sample/sample_audvis_filt-0-40_raw.fif' event_fname = data_path + '/MEG/sample/sample_audvis_filt-0-40_raw-eve.fif' event_id = 1 tmin = -0.2 tmax = 0.5 # Setup for reading the raw data raw = io.read_raw_fif(raw_fname) events = mne.read_events(event_fname) channel = 'MEG 1332' # include only this channel in analysis include = [channel] ############################################################################### # Read epochs for the channel of interest picks = mne.pick_types(raw.info, meg=False, eog=True, include=include, exclude='bads') event_id = 1 reject = dict(grad=4000e-13, eog=150e-6) epochs1 = mne.Epochs(raw, events, event_id, tmin, tmax, picks=picks, baseline=(None, 0), reject=reject) condition1 = epochs1.get_data() # as 3D matrix event_id = 2 epochs2 = mne.Epochs(raw, events, event_id, tmin, tmax, picks=picks, baseline=(None, 0), reject=reject) condition2 = epochs2.get_data() # as 3D matrix condition1 = condition1[:, 0, :] # take only one channel to get a 2D array condition2 = condition2[:, 0, :] # take only one channel to get a 2D array ############################################################################### # Compute statistic threshold = 6.0 T_obs, clusters, cluster_p_values, H0 = \ permutation_cluster_test([condition1, condition2], n_permutations=1000, threshold=threshold, tail=1, n_jobs=1) ############################################################################### # Plot times = epochs1.times plt.close('all') plt.subplot(211) plt.title('Channel : ' + channel) plt.plot(times, condition1.mean(axis=0) - condition2.mean(axis=0), label="ERF Contrast (Event 1 - Event 2)") plt.ylabel("MEG (T / m)") plt.legend() plt.subplot(212) for i_c, c in enumerate(clusters): c = c[0] if cluster_p_values[i_c] <= 0.05: h = plt.axvspan(times[c.start], times[c.stop - 1], color='r', alpha=0.3) else: plt.axvspan(times[c.start], times[c.stop - 1], color=(0.3, 0.3, 0.3), alpha=0.3) hf = plt.plot(times, T_obs, 'g') plt.legend((h, ), ('cluster p-value < 0.05', )) plt.xlabel("time (ms)") plt.ylabel("f-values") plt.show()