DTI Task Card

Version 1.50 for VA15/VA21

This document describes how to use the task card for Diffusion Tensor Imaging (DTI Task Card) on a SIEMENS NUMARIS 4 satellite console. This task card allows visualization of diffusion tensor imaging data and white matter fiber tracking. A general knowledge of MRease usage is assumed.

Contents[top]

[down]Installation
[down]Detailed Instructions

[down]Loading Image Data
[down]General Tensor Viewing
[down]Tractography
[down]Miscellanies

[down]Known Issues
[down]References
[down]Acknowledgment
[down]Further Information

Installation[top]

Before installation please check if the following software/hardware requirements are met:

Also, please read the license and be aware of the following issues before installing the DTI Task Card software:

To install/upgrade/uninstall the DTI Task Card, run the setup file "DTI_TaskCard_VAXX.exe" that matches your version and follow appropriate steps.

Detailed Instructions[top]

Loading Image Data

Open the Patient Browser. Select the series of the original diffusion data to be used for diffusion tensor map calculation and visualization. Then click on the DTI button on the toolbar of the Patient Browser and select the appropriate type of sequence to load the data into the DTI Task Card.

After data is loaded and calculated, the diffusion tensors can now be visualized in different patterns and white matter fiber tracking (tractography) can also be performed.

load

General Tensor Viewing[top]

Viewing Mode Buttons

Select between Tensor or Tractography viewing mode.

Tensor Tensor viewing mode. Tensor View
Tractography Tractography viewing mode. Tractography View

Tool Buttons for Tensor Viewing[top]

View View
View 1:1 1:1. Set the current viewpage the same size of the view port.
View 4:1 4:1. Split view port to allow 4 viewpages shown together.
View 9:1 9:1. Similar to above.
View 16:1 16:1. Similar to above.
Zoom in Zoom In. Zoom in the current selected image by a factor of 2.
Zoom out Zoom Out. Zoom out the current selected image by a factor of 2.
Zoom to Zoom ... Zoom the current selected image by an arbitrary factor chosen by user.
Restore Restore. Restore the current image's size and position.
Restore all Restore All. Restore all the images' size and position.


Image image
BoxoidEllipsoid
Plain ColorPlain Grayscale
Boxoid, Ellipsoids, Plain Color or Plain Grayscale. Set the rendering object to Boxoid or Ellipsoid for the visualization of diffusion tensor, or just plain color or grayscale map. The small dark arrow on the right bottom of the button indicates that a drop-down menu will be shown if clicked, allowing to select the object.
Color Sphere Color Sphere. Show the color sphere indicating the direction-color coding for visualization.
Unnormalized Scaling Unnormalized Scaling . Set unnormalized scaling for rendering of the diffusion tensor object. That is, use the three eigenvalues as the scaling factors for Boxoid or Ellipsoid object.
This button is only enabled when Boxoid or Ellipsoid is chosen.
Parallel Parallel Viewing. Set the projection mode to Parallel or Prospective.
Interpolate Interpolate. Turn on/off the interpolation for Plain Color or Plain Grayscale map.
Slider Noise Threshold. Manually set the noise threshold for rendering (valid from 0 to 100). Noise threshold is used to determine background in Low b image.
Auto Threshold Autoset Noise Threshold. Automatically set the noise threshold as the mean value plus 6 times standard deviation of low b background.


Map Map
FA FA. Set Fractional Anisotropy as the weighting factor for current visualization/maps.
E2-E3 E2-E3. Set E2 minus E3 as the weighting factor for current visualization/maps. E1, E2 and E3 represent the three eigen-values of the diffusion tensor at each voxel.
E1 E1. Set E1 as the weighting factor for current maps. Only generic grayscale map is valid at this mode.
E2 E2. Set E2 as the weighting factor for current maps. Only generic grayscale map is valid at this mode.
E3 E3. Set E3 as the weighting factor for current maps. Only generic grayscale map is valid at this mode.


Patient Patient
Open Load Pixel Data From File. Load pixel data from an existing .bshort file.
Note: This function is very preliminary and not yet recommended to use.
Close Close Patient. Close the current patient.
New Series Write New Series. Write new series into database. There will be a pop-up dialog allowing to selection what maps (FA, E1-E3, etc.) to write. The new images can be loaded into the Viewing Task Card.
This button is only valid when data is loaded from database (not .bshort file).

Note:

  • All of the above commands except the ones in "Patient" category can be found in the main menu on top of the task card.

  • Move the mouse cursor over each button to show its tooltip. Tooltip can only be shown when the button is not grayed.

  • Loading a new series (new patient data) will close the current loaded patient and clear all the previously rendered images.

Mouse[top]

Move At this cursor, hold left button and drag to move the image.
Zoom At this cursor, hold left button and drag to zoom the image.
Rotate Hold right button and drag to rotate the image.
Hold middle button and drag to change windowing level of the image. (Note: Color and grayscale windowing are independent).
Right-click to bring up popup menu for more commands. Popup Menu

Tractography[top]

Fiber Tracking Steps

1. Switch to Tractography viewing mode. Zoom/Pan/Rotate the image to appropriate position for better viewing. (Similar to Tensor viewing mode).

Use the IS/LR/AP sliders on the upper right corner of the panel to select different slices.
Tractography View
2. Hold Ctrl Key + Left Mouse Button to select Seed Region (or Region Of Interest). Select ROI
3. Release Left Mouse Button and the program will do fiber tracking starting from the selected seed region.
(NOTE: If Ctrl key is released before Left Mouse Button, the selected region will be canceled and fiber tracking will not be performed.)
Result
Tips:
Hold Shift Key + Left Mouse Button to "test-track" in the real time.
Click right mouse button to bring up popup menu for the COMPLETE set of commands, such as:
  • Enable/disable fast interactive viewing.
  • Select different maps.
  • Hide/Show/Delete fibers.
  • Changing fiber tracking parameters and rendering parameters.
  • Hide/Show slices and axes.
Some of the commands are not available from the menu bar or the tool buttons.
Popup Menu

Sample Images[top]

Fiber tracking visualization in the DTI Task Card. Sample1 Fiber tracking images saved to the database by DTI Task Card and loaded in the Viewing task card later on. Sample2

Miscellanies[top]

Click the copyright texts on the lower right corner of the screen to bring up About window with version info and link to this online documentation.

about

Known Issues[top]

This software is not an official release and it is not as tightly integrated into MRease as an official SIEMENS task card. Due to this reason, the following known issues may or may not be solved in the near future.

References[top]

The algorithms used for fiber tracking are based on the following literature:

  1. Mori S, Crain BJ, Chacko VP, van Zijl PC.
    Three-dimensional tracking of axonal projections in the brain by magnetic resonance imaging.
    Ann Neurol 1999; 45: 265-269.(PubMed abstract)
  2. Basser PJ, Pajevic S, Pierpaoli C, Duda J, Aldroubi A.
    In vivo fiber tractography using DT-MRI data.
    Magn Reson Med 2000;44:625-632.(PubMed abstract)
  3. B. Stieltjes, W.E. Kaufmann, P.C. van Zijl, K. Fredericksen, G.D. Pearlson, M. Solaiyappan and S.Mori.
    Diffusion tensor imaging and axonal tracking in the human brainstem.
    Neuroimage 14 (2001), pp.723-735.(PubMed abstract)
  4. Mori S, Van Zijl PC.
    Fiber tracking: principles and strategies - a technical review.
    NMR Biomed. 2002 Nov-Dec;15(7-8):468-80.(PubMed abstract)

Acknowledgement[top]

The DTI Task Card would not exist without prior idea and suggestion from David Tuch.

Further Information[top]

If you have questions or problems about the DTI Task Card, please contact Ruopeng Wang <rpwang@nmr.mgh.harvard.edu>.