Welcome to the Dickerson Lab: High Resolution Hippocampal Imaging
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We continue to pursue the development, enhancement, and application of new methods for imaging and measuring aspects of the structure, function, and connectivity of the human hippocampus and medial temporal lobe brain regions at unprecedented levels of detail.
Since mid-2005, we have undertaken a collaborative development project with investigators in the Martinos Center for Biomedical Imaging and MIT, generously supported in part by the P41 NCRR resource grant, in which we are developing, validating, and applying methods for fMRI studies at resolutions as high as 1mm isotropic (3T) and 0.95mm isotropic (7T) and structural MRI studies at resolutions of 500um isotropic and 380um in-plane (3T and 7T). An essential part of these studies are the ultrahigh-resolution collaborative team (see "People"). Work is ongoing with local and distant collaborators to share methods as they are being developed.
With our collaborators, we recently presented and published a novel method for the automated segmentation of hippocampal subregions using ultra-high resolution data collected on cognitively intact younger and older individuals. This work was published in 2009 in Medical Image Computing; the paper can be obtained from the publications link above.