Optical Molecular Imaging Lab
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Publications

  1. Chongzhao Ran, Robert Moir, and Anna Moore, A curcumin analogue as a “smart” fluorescent probe with potential capacity for in vivo imaging the full course of amyloidosis of Alzheimer’s disease, Submitted.
  2. Wang P, Yigit MV, Ran C, Ross A, Wei L, Dai G, Medarova Z, Moore A.A Theranostic Small Interfering RNA Nanoprobe Protects Pancreatic Islet Grafts From Adoptively Transferred Immune Rejection. Diabetes. 2012 Aug 24. [Epub ahead of print]
  3. Chongzhao Ran, Zhaoda Zhang, Jacob M. Hooker, Anna Moore. In vivo photoactivation without "light": use of Cherenkov radiation to overcome the penetration limit of light. Molecular Imaging and Biology. 2012, 14(2):156-62
  4. Chongzhao Ran, Anna Moore, Spectral unmixing imaging of “smart” fluorescent probes: an application for the real-time report of amyloid beta species in Alzheimer’s disease, Molecular Imaging and Biology, 2012,14(3): 293-300.
  5. Chongzhao Ran, Anna Moore, Non-conjugated Small Molecule FRET for Differentiating Monomers from High Molecular Weight Amyloid beta Species, PLoS One. 2011 Apr 29;6(4):e19362.
  6. Chongzhao Ran, Xiaoyin Xu, Pamela Pantazopoulos, Zdravka Medarova, Brian J. Bacskai, Anna Moore, Design, Synthesis and Testing of Curcumin Based “Smart” Near Infrared Probes for in vivo Detection of Amyloid-β Plaques in Transgenic Animal Model,  J. Amer. Chem. Soc., 2009, 131 (42), 15257–15261.
  7. Chongzhao Ran, Ronald G. Harvey, A practical approach for preparing Carbon-13 Labeled Benzo[a]pyrene and Benzo[a]pyren-7,8-dione, Tetrahedron letters, 2008, 49, 4531-4533.
  8. Chongzhao Ran, Qing Dai, and Ronald G. Harvey, Strategies for Synthesis of Adducts of o-Quinone Metabolites of Carcinogenic Polycyclic Aromatic Hydrocarbons with 2'-Deoxyribonucleosides, Journal of Organic Chemistry, 2008, 73 (3), 992 -1003.
  9. Chongzhao Ran, Pamela Pantazopoulos, Zdravka Medarova, Anna Moore, Synthesis and Testing of Beta-Cell-Specific Streptozotocin-Derived Near-Infrared Imaging Probes,  Angewandte Chemie International Edition, 2007, 46(47), 8998-9001.
  10. Zhang Y, Chongzhao Ran, Zhou G, Sayre LM.  Highly potent 3-pyrroline mechanism-based inhibitors of bovine plasma amine oxidase and mass spectrometric confirmation of cofactor derivatization. Bioorg Med Chem. 2007, 15(4):1868-77.
  11. Qing Dai, Chongzhao Ran, and Ronald G. Harvey, Regioselective arylation of 2¢-deoxyribonucleosides on amido or imino  sites by copper(II)-mediated direct coupling with arylboronic acids,  Tetrahedron,  2006, 62, 1764.
  12. Jisook Kim, Yuming Zhang, Chongzhao Ran, Lawrence M Sayre, Inactivation of Bovine Plasma Amine Oxidase by Haloallylamine Analogies.  Bioorganic & Medicinal Chemistry, 2006, 14, 1444.
  13. Ronald G. Harvey, Qing Dai, Chongzhao Ran, Keunpoong Lim, Ian Blair, Trevor M. Penning,  Synthesis of Adducts of Active Metabolites of Carcinogenic Polycyclic Aromatic Hydrocarbons with 2'-deoxyribonucleosides,  Polycyclic Aromatic Compounds,  2005, 25 (5), 371-391.
  14. Chongzhao Ran, Qing Dai, Ronald G. Harvey, Efficient synthesis of N6-aryl-2'-deoxyadenosines via copper-mediated direct coupling of aryl halide with 2'-deoxyadenosine.  Journal of Organic Chemistry, 2005, 70(9), 3724-26.
  15. Qing Dai, Chongzhao Ran, Ronald G. Harvey, Synthesis of adducts of o-quinone metabolites of Carcinogenic polycyclic aromatic hydrocarbons with 2’-deocyadenosine and 2’-deoxyuanosine.  Organic Letters, 2005, 7(6), 999-1002.
  16. Ronald G. Harvey; Qing Dai; Chongzhao Ran; Sridhar R. Gopishetty; Trevor M. Penning.  Efficient New Syntheses of Metabolites of PAH ortho-Quinones and their Adducts with 2’-deocyribonucleooside adducts.  Polycyclic Aromatic Compounds. 2004, 24(4-5), 257-269.
  17. Ronald G. Harvey; Qing Dai; Chongzhao Ran; Trevor M.  Penning. Synthesis of the o-Quinones and Other Oxidized Metabolites of Polycyclic   Aromatic Hydrocarbons Implicated in Carcinogenesis.  Journal of Organic Chemistry 2004, 69(6), 2024-2032.
  18. Ronald G. Harvey; Qing Dai; Chongzhao Ran; Trevor M.  Penning.  Efficient syntheses of the active metabolites of carcinogenic polycyclic aromatic hydrocarbons. ACS Symposium Series 865 (Aldo-Keto Reductases and Toxicant Metabolism), 2004, 115-126.
  19. Chongzhao Ran, Weihan Zhang, Lawrence M. Sayre,  Protein crosslinking and efficient synthesis of 2E, 4E, 6E-dodecatrienal. Tetrahedron Letters, 2004, 45(24), 7851-53.
  20. Chongzhao Ran, Genjin Yang, Taizhi Wu, Meihua Xie, A Novel Reaction of Secondary Nitro Compounds with Nitrite. A New Approach to Prepare a-Oximinoketones ,  Tetrahedron Letters. 2003. 44, 8061-8062.
  21. Chongzhao Ran, Meihua Xie, Progress in Class III antiarrhythmic agents, Chinese Journal of Pharmaceuticals, 2001, 32(10), 474-479.
  22. Chongzhao Ran, Guo-Ping Wang, Tai-Zhi Wu, Mei-Hua Xie, A New Convenient Approach to Preparation of 5 Or 6 Or 7-Nitro-1,2,3,4- Tetrahydroisoquinolines and 2-alkylsulfonyl-5 Or 6 Or 7-Nitro-1,2,3,4-tetrahydroisoquinolines,  Synthetic. Communication, 2000, 30(9), 1581-1587.
  23. Liu Hui; Ran Chong-zhao; Xia Lin; Ni Pei-zhou, Synthesis and anti alpha-adrenoceptor activity in vitro of 4-((4-((2-substitutedphenoxy)ethyl)-1-piperazinyl) methyl)- 1,2-dihydro-quinoline-2-one
  24. compounds.  Yao xue xue bao ( Acta pharmaceutica Sinica), 2002 ,  37(3),  181-5.
  25. Chongzhao Ran, Lin Xia, Peizhou Ni, Synthesis and bioactivities studies of some DDPH analogues,  Journal of China Pharmaceutical University, 2000, 31(4), 246-250; 
  26. Chongzhao Ran, Taizhi Wu, Meihua Xie, A new approach to prepare substituted phenylethylamine, Chinese Chemical Letter, 2000, 11(10), 856-857.
  27. Chong-Zhao Ran, Lin Xia, Pei-Zhou Ni, The Influence of Ketones on the Formation of Symmetrical Secondary Amine: A New Method for Preparation of N,N-Bis-(dimethoxyphenylethyl)amine,  Chinese Chemical Letter, 1999, 10(11), 894-860.
  28. Zhi-Gang Ding, Wei-Heng Ren, Dong-Dong Luo, Chong-Zhao Ran, Study of artificial enzymes by synthesis of Bis-(6-O-m- carbonylbenzenesulfonyl)-β- CD with nickelous chloride,  Huaxue Yanjiu Yu Yingyong, (Chemical Research and Application) 1996, 8(1):103~106.