Pract Radiat Oncol. 2013 Jul 1;3(3):186193 doi: 10.1016/j.prro.2012.11.002.

Prospective Assessment of an Atlas-Based Intervention Combined With Real-Time Software Feedback in Contouring Lymph Node Levels and Organs-at-Risk in the Head and Neck: Quantitative Assessment of Conformance to Expert Delineation

Awan M, Kalpathy-Cramer J, Gunn GB, Beadle BM, Garden AS, Phan J, Holliday E, Jones WE 3rd, Maani E, Patel A, Choi J, Clyburn V, Tantiwongkosi B, Rosenthal DI, Fuller CD.

Abstract

PURPOSE: A number of studies have previously assessed the role of teaching interventions to improve organ-at-risk (OAR) delineation. We present a preliminary study demonstrating the benefit of a combined atlas and real time software based-feedback intervention to aid in contouring of OARs in the head and neck.
METHODS AND MATERIALS: The study consisted of a baseline evaluation, a real-time feedback intervention, atlas presentation, and a follow-up evaluation. At baseline evaluation, 8 resident observers contoured 26 organs-at-risk on a computed tomography scan without intervention or aid. They then received feedback comparing their contours both statistically and graphically to a set of atlas-based expert contours. Additionally, they received access to an atlas to contour these structures. The resident observers were then asked to contour the same 26 organs-at-risk on a separate computed tomography scan with atlas access. In addition, 6 experts (5 radiation oncologists specializing in the head and neck, and 1 neuroradiologist) contoured the 26 organs-at-risk on both scans. A STAPLE composite of the expert contours was used as a gold-standard set for analysis of organs-at-risk contouring.
RESULTS: Of the 8 resident observers who initially participated in the study, 7 completed both phases of the study. Dice Similarity Coefficients (DSCs) were calculated for each user-drawn structure relative to the expert STAPLE composite for each structure. Mean DSC across all structures increased between Phase 1 and Phase 2 for each resident observer demonstrating a statistically significant improvement in overall OAR-contouring ability (p CONCLUSIONS: Our data suggest that a combined atlas and real-time feedback-based educational intervention detectably improves contouring of OARs in the head and neck.

PMID: 23853674