Opt Lett. 2013 May 1;38(9):1440-2 2013 May 02.

Fluorescence lifetime detection in turbid media using spatial frequency domain filtering of time domain measurements

Kumar AT.

Abstract

It is demonstrated that high spatial frequency filtering of time domain fluorescence signals can allow efficient detection of intrinsic fluorescence lifetimes from turbid media and the rejection of diffuse excitation leakage. The basis of this approach is the separation of diffuse fluorescence signals into diffuse and fluorescent components with distinct spatiotemporal behavior.

PMID: 23632511