Magnetic resonance imaging is a powerful non-invasive technology that provides a unique window to the structure and the function of the body, with high resolution, speed, and biological contrast.  Our lab focuses on the development of new hyperpolarization methods and MRI-based tools which rethink conventional approaches to MRI scanner construction.  This includes the development of tools and techniques for robust low-magnetic-field implementations of MRI focused on brain imaging, including new opportunities provided by free-radical injury markers paired with in vivo Overhauser DNP at low magnetic field.